Evaluating the Role and Impact of International Collaboration and Partnerships on the Control, Prevention, and Elimination of Parasitic Diseases: A Global Health Perspective
Australian Journal of Biomedical Research, 1(2), 2025, aubm009, https://doi.org/10.63946/aubiomed/17426
Publication date: Nov 18, 2025
ABSTRACT
Parasitic diseases continue to represent a significant public health challenge, particularly in tropical and subtropical regions, where they disproportionately affect low- and middle-income countries. Despite significant advancements in global collaborations, diseases such as malaria, schistosomiasis, and leishmaniasis continue to present substantial challenges. This study evaluates the role of international collaborations such as the World Health Organization (WHO) and the Global Fund, alongside bilateral and multilateral initiatives, including the U.S. President's Malaria Initiative (PMI) in managing, preventing, and eliminating parasitic diseases, highlighting the successes, challenges, and potential areas for improvement within these partnerships. Critical challenges to effective collaborations, such as political instability, economic disparities, cultural barriers, and resource inequities were identified. Additionally discussed are the necessity of developing local skills, promoting innovative financing methods for projects, and ensuring their sustainability. Moreover, the necessity of a unified global health governance framework and sustained commitments to ensure that multinational collaborations yield enduring impacts were emphasized. However, policy recommendations such as prioritizing equity, and addressing the root causes of parasite infections aimed at enhancing international cooperation should be embraced in order to achieve sustainable health improvements. The findings suggest that ongoing global cooperation, combined with improvements in technology, funding, and resource allocation, is crucial for the total elimination of parasitic diseases and the advancement of health equity worldwide.
KEYWORDS
Parasitic Diseases Global Health Public Health International Collaboration Infectious Diseases Disease Control Health Equity Neglected Tropical Diseases
CITATION (Vancouver)
Nwokedi VU, Akanbi OO, Ayo-ige BA, Aderounmu RA, Kassim NO, Aneke OB, et al. Evaluating the Role and Impact of International Collaboration and Partnerships on the Control, Prevention, and Elimination of Parasitic Diseases: A Global Health Perspective. Australian Journal of Biomedical Research. 2025;1(2):aubm009. https://doi.org/10.63946/aubiomed/17426
APA
Nwokedi, V. U., Akanbi, O. O., Ayo-ige, B. A., Aderounmu, R. A., Kassim, N. O., Aneke, O. B., Inumimo, O., Ilesanmi, O. J., Luper, T., & Farinde, T. D. (2025). Evaluating the Role and Impact of International Collaboration and Partnerships on the Control, Prevention, and Elimination of Parasitic Diseases: A Global Health Perspective. Australian Journal of Biomedical Research, 1(2), aubm009. https://doi.org/10.63946/aubiomed/17426
Harvard
Nwokedi, V. U., Akanbi, O. O., Ayo-ige, B. A., Aderounmu, R. A., Kassim, N. O., Aneke, O. B., . . . Farinde, T. D. (2025). Evaluating the Role and Impact of International Collaboration and Partnerships on the Control, Prevention, and Elimination of Parasitic Diseases: A Global Health Perspective. Australian Journal of Biomedical Research, 1(2), aubm009. https://doi.org/10.63946/aubiomed/17426
AMA
Nwokedi VU, Akanbi OO, Ayo-ige BA, et al. Evaluating the Role and Impact of International Collaboration and Partnerships on the Control, Prevention, and Elimination of Parasitic Diseases: A Global Health Perspective. Australian Journal of Biomedical Research. 2025;1(2), aubm009. https://doi.org/10.63946/aubiomed/17426
Chicago
Nwokedi, Vivian Ukamaka, Olukunle O. Akanbi, Blessing Ayodele Ayo-ige, Rahmatallahi Ajike Aderounmu, Nimotalai Olusola Kassim, Oluchi Beatrice Aneke, Ogunmekan Inumimo, Olawale Johnson Ilesanmi, Tyoakosu Luper, and Tobi David Farinde. "Evaluating the Role and Impact of International Collaboration and Partnerships on the Control, Prevention, and Elimination of Parasitic Diseases: A Global Health Perspective". Australian Journal of Biomedical Research 2025 1 no. 2 (2025): aubm009. https://doi.org/10.63946/aubiomed/17426
MLA
Nwokedi, Vivian Ukamaka et al. "Evaluating the Role and Impact of International Collaboration and Partnerships on the Control, Prevention, and Elimination of Parasitic Diseases: A Global Health Perspective". Australian Journal of Biomedical Research, vol. 1, no. 2, 2025, aubm009. https://doi.org/10.63946/aubiomed/17426
REFERENCES
- Pisarski K. The global burden of disease of zoonotic parasitic diseases: top 5 contenders for priority consideration. Trop Med Infect Dis. 2019;4(1):44. https://doi.org/10.3390/tropicalmed4010044
- Centers for Disease Control and Prevention. Parasites. CDC twenty four seven. Saving Lives, Protecting People; 2024 Nov 14. Available from: https://www.cdc.gov/parasites/about/index.html#:~:text=Parasitic%20Infections,burden%20placed%20on%20entire%20countries.
- World Health Organization. Malaria; 2024 Dec 11. Available from: https://www.who.int/news-room/fact-sheets/detail/malaria
- World Health Organization. World Malaria Report 2020: 20 years of global progress & challenges. 2020 Nov 30. Available from: https://www.who.int/teams/global-malaria-programme/reports/world-malaria-report-2020
- The Global Fund, Gavi, World Health Organization. Impactful Partnership in Action: Global Fund, Gavi and WHO: The Global Fund; 2024 Dec. Available from: https://www.theglobalfund.org/media/15327/partnership_impactful-partnership-gavi-global-fund-who_report_en.pdf
- World Health Organization. Global programme to eliminate lymphatic filariasis: progress report, 2023. Wkly Epidemiol Rec. 2024;99(40):565-76. Available from: https://www.who.int/publications/i/item/who-wer-9940-565-576
- Isaev V. The Global Burden of Parasitic Diseases: Prevalence, Mortality and Economic Costs. Bio Med. 2024;16(12):760. Available from: https://www.walshmedicalmedia.com/open-access/the-global-burden-of-parasitic-diseases-prevalence-mortality-and-economic-costs.pdf
- Abou-El-Naga IF. Demographic, socioeconomic and environmental changes affecting circulation of neglected tropical diseases in Egypt. Asian Pac J Trop Med. 2015;8(11):881-8. https://doi.org/10.1016/j.apjtm.2015.10.015
- Bowers SF, Sonnet F, Downs JA. Schistosomiasis: a neglected cause of infertility in females and males. Curr Opin Infect Dis. 2025;Publish Ahead of Print. https://doi.org/10.1097/qco.0000000000001127
- Rinaldo D, Perez-Saez J, Vounatsou P, Utzinger J, Arcand JL. The economic impact of schistosomiasis. Infect Dis Poverty. 2021;10(1):134. https://doi.org/10.1186/s40249-021-00919-z
- Liang S, Seto EY, Remais JV, Zhong B, Yang C, Hubbard A, et al. Environmental effects on parasitic disease transmission exemplified by schistosomiasis in western China. Proc Natl Acad Sci U S A. 2007;104(17):7110-5. https://doi.org/10.1073/pnas.0701878104
- World Health Organization. Leishmaniasis; 2023 Jan 12. Available from: https://www.who.int/news-room/fact-sheets/detail/leishmaniasis
- Andrade MV, Noronha K, Diniz BP, Guedes G, Carvalho LR, Silva VA, et al. The economic burden of malaria: a systematic review. Malar J. 2022;21(1):283. https://doi.org/10.1186/s12936-022-04303-6
- World Health Organization. Malaria: World malaria report 2019. Available from: https://www.who.int/teams/global-malaria-programme/reports/world-malaria-report-2019
- World Health Organization. Soil-transmitted helminth infections; 2023 Jan 18. Available from: https://www.who.int/news-room/fact-sheets/detail/soil-transmitted-helminth-infections
- Chen J, Gong Y, Chen Q, Li S, Zhou Y. Global burden of soil-transmitted helminth infections, 1990-2021. Infect Dis Poverty. 2024;13(05):68-77. https://doi.org/10.1186/s40249-024-01238-9
- World Health Organization. Schistosomiasis; 2023 Feb 1. Available from: https://www.who.int/news-room/fact-sheets/detail/schistosomiasis
- World Health Organization. Lymphatic filariasis; 2025 Jan 5. Available from: https://www.who.int/health-topics/lymphatic-filariasis
- Tawana M, Onyiche TE, Ramatla T, Thekisoe O. A ‘One Health’perspective of Africa-wide distribution and prevalence of Giardia species in humans, animals and waterbodies: a systematic review and meta-analysis. Parasitology. 2023;150(9):769-80. https://doi.org/10.1017/s0031182023000513
- Centers for Disease Control and Prevention. Giardiasis. Saving Lives, Protecting People; 2023 Sep 26. Available from: https://www.cdc.gov/parasites/giardia/index.html
- World Health Organization. Chagas disease (also known as American trypanosomiasis); 2025 Apr 2. Available from: https://www.who.int/news-room/fact-sheets/detail/chagas-disease-(american-trypanosomiasis)
- Centers for Disease Control and Prevention. About Chagas Disease. Saving Lives, Protecting People; 2025 Aug 25. Available from: https://www.cdc.gov/parasites/chagas/gen_info/detailed.html
- World Health Organization. Onchocerciasis; 2025 Jan 29. Available from: https://www.who.int/news-room/fact-sheets/detail/onchocerciasis
- Inceboz T. Epidemiology and ecology of leishmaniasis. Curr Top Negl Trop Dis. 2019;10. https://doi.org/10.5772/intechopen.86359
- World Health Organization. Trypanosomiasis, human African (sleeping sickness); 2023 May 2. Available from: https://www.who.int/news-room/fact-sheets/detail/trypanosomiasis-human-african-(sleeping-sickness)
- World Health Organization. Defeating neglected tropical diseases through enhanced collaboration; 2024. Available from: https://www.who.int/teams/control-of-neglected-tropical-diseases/collaboration
- World Health Organization. Partnership established to advance WHO’s road map for neglected tropical diseases 2021–2030; 2024 Dec 11. Available from: https://www.who.int/news/item/11-12-2024-partnership-established-to-advance-who-s-road-map-for-neglected-tropical-diseases-2021-2030
- World Health Organization. Global programme to eliminate lymphatic filariasis: progress report, 2023. Wkly Epidemiol Rec. 2024;99(40):565–76.
- World Health Organization. Health emergencies. Available from: https://www.who.int/our-work/health-emergencies
- Centers for Disease Control and Prevention. Global malaria activities. 2024 Apr 04. Available from: https://www.cdc.gov/malaria/php/public-health-strategy/global-activities.html
- U.S. President's Malaria Initiative. 2020 annual report. Washington, D.C.: U.S. Agency for International Development; 2020. Available from: https://reliefweb.int/report/world/president-s-malaria-initiative-14th-annual-report-congress-april-2020
- The Global Fund. About the Global Fund. 2025, September 10. Available from: https://www.theglobalfund.org/en/about-the-global-fund/#:~:text=Our%20Mission,overcome%20the%20deadliest%20disease%20threats.
- Watts C. Neglected tropical diseases: a DFID perspective. PLoS Negl Trop Dis. 2017;11(4):e0005492. https://doi.org/10.1371/journal.pntd.0005492
- Bill & Melinda Gates Foundation. Our role. Available from: https://www.gatesfoundation.org/about/our-role
- Sikaala CH, Dlamini B, Lungu A, Fakudze P, Chisenga M, Siame CL, et al. Malaria elimination and the need for intensive inter-country cooperation: a critical evaluation of regional technical co-operation in Southern Africa. Malar J. 2024;23(1):62. https://doi.org/10.1186/s12936-024-04891-5
- Nit M. The role of international cooperation in controlling infectious diseases. J Infect Dis Med Microbiol. 2024;8(3):203. Available from: https://www.alliedacademies.org/articles/the-role-of-international-cooperation-in-controlling-infectious-diseases.pdf
- Parkhurst J, Ghilardi L, Webster J, Snow RW, Lynch CA. Competing interests, clashing ideas and institutionalizing influence: insights into the political economy of malaria control from seven African countries. Health Policy Plan. 2021;36(1):35-44. https://doi.org/10.1093/heapol/czaa166
- UNICEF. Ongoing conflict disrupts efforts to control malaria and threatens health of millions of children in Sudan. 2025 Apr 25. Available from: https://www.unicef.org/sudan/press-releases/ongoing-conflict-disrupts-efforts-control-malaria-and-threatens-health-millions
- Ung L, Stothard JR, Phalkey R, Azman AS, Chodosh J, Hanage WP, et al. Towards global control of parasitic diseases in the Covid-19 era: One Health and the future of multisectoral global health governance. Adv Parasitol. 2021;114:1-26. https://doi.org/10.1016/bs.apar.2021.08.007
- Kaminsky R, Mäser P. Global impact of parasitic infections and the importance of parasite control. Front Parasitol. 2025;4:1546195. https://doi.org/10.3389/fpara.2025.1546195
- Parker M, Allen T. De-politicizing parasites: reflections on attempts to control the control of neglected tropical diseases. Med Anthropol. 2014;33(3):223-39. https://doi.org/10.1080/01459740.2013.831414
- Brown GW, Rhodes N, Tacheva B, Loewenson R, Shahid M, Poitier F. Challenges in international health financing and implications for the new pandemic fund. Global Health. 2023;19(1):97. https://doi.org/10.1186/s12992-023-00999-6
- Hanson K, Brikci N, Erlangga D, Alebachew A, De Allegri M, Balabanova D, et al. The Lancet Global Health Commission on financing primary health care: putting people at the centre. Lancet Glob Health. 2022;10(5):e715-72. https://doi.org/10.1016/s2214-109x(22)00005-5
- Onwuliri CO, Anosike JC, Oguoma C, Onwuliri VA, Nwoke BE, Dozie IN, et al. The Impact of Cultural Behaviours, Local Beliefs, and Practices on Emerging Parasitic Diseases in Tropical Africa. Negro Educ Rev. 2005;56(4):311. Available from: https://eric.ed.gov/?id=EJ751093
- Ajegena BK, Oti VB. The challenges of using insecticides treated nets (ITNs) in curbing malaria in Nigeria: a 2000–2018 systematic review. J Infect Dis Epidemiol. 2020;6(4). https://doi.org/10.23937/2474-3658%2F1510140
- Aubel J, Chibanda D. The neglect of culture in global health research and practice. BMJ Glob Health. 2022;7(9). https://doi.org/10.1136/bmjgh-2022-009914
- Buzeti T, Madureira Lima J, Yang L, Brown C. Leaving no one behind: health equity as a catalyst for the sustainable development goals. Eur J Public Health. 2020;30(Supplement_1):i24-7. https://doi.org/10.1093/eurpub/ckaa033
- Gustavsen K, Sodahlon Y, Bush S. Cross-border collaboration for neglected tropical disease efforts—Lessons learned from onchocerciasis control and elimination in the Mano River Union (West Africa). Global Health. 2016;12(1):44. https://doi.org/10.1186/s12992-016-0185-5
- Nájera JA, González-Silva M, Alonso PL. Some lessons for the future from the Global Malaria Eradication Programme (1955–1969). PLoS Med. 2011;8(1):e1000412. https://doi.org/10.1371/journal.pmed.1000412
- Boussinesq M. Onchocerciasis control: biological research is still needed. Parasite. 2008;15(3):510-4. https://doi.org/10.1051/parasite/2008153510
- The Global Fund. Information Note Malaria: The Global Fund; 2022 Jul 29. Available from: https://www.theglobalfund.org/media/4768/core_malaria_infonote_en.pdf
- van Dale D, Lemmens L, Hendriksen M, Savolainen N, Nagy P, Marosi E, et al. Recommendations for effective intersectoral collaboration in health promotion interventions: results from joint action CHRODIS-PLUS work package 5 activities. Int J Environ Res Public Health. 2020;17(18):6474. https://doi.org/10.3390/ijerph17186474
- World Health Organization. Ending the neglect to attain the sustainable development goals: a road map for neglected tropical diseases 2021–2030: overview. 2020.
- Al-Worafi YM. Healthcare Services in Developing Countries. In: Handbook of medical and health sciences in developing countries: Education, practice, and research. Cham: Springer International Publishing; 2023. p. 1-21. https://doi.org/10.1007/978-3-030-74786-2_216-1
- Le Gargasson JB, Salomé B. The role of innovative financing mechanisms for health. World Health Report. 2010. Available from: https://cdn.who.int/media/docs/default-source/health-financing/technical-briefs-background-papers/innovativebp12final.pdf
- GHIT Fund. Annual report 2025. Available from: https://www.ghitfund.org/assets/othermedia/annual_report_2024_eng.pdf
- Laurens MB. RTS, S/AS01 vaccine (Mosquirix™): an overview. Hum Vaccin Immunother. 2020;16(3):480-9. https://doi.org/10.1080/21645515.2019.1669415
- Oroxom R, Glassman A, McDonald L. Structuring and funding development impact bonds for health: nine lessons from Cameroon and beyond. Center for Global Development. 2018 Jan 26. Available from: https://www.cgdev.org/sites/default/files/structuring-funding-development-impact-bonds-for-health-nine-lessons.pdf
- de Souza Rodrigues D. Digital Health Framework to Combating Neglected Tropical Diseases [Doctoral dissertation]. Universidade Federal do Rio de Janeiro; 2024. Available from: https://w1files.solucaoatrio.net.br/atrio/ufrj-pep_upl//THESIS/10004423/douglas_de_souza_rodrigues_20241016110609186.pdf
- Srivastava V, Kumar R, Wani MY, Robinson K, Ahmad A. Role of artificial intelligence in early diagnosis and treatment of infectious diseases. Infect Dis (Lond). 2025;57(1):1-26. https://doi.org/10.1080/23744235.2024.2425712
- Danasekaran R. One health: a holistic approach to tackling global health issues. Indian J Community Med. 2024;49(2):260-3. https://doi.org/10.4103/ijcm.ijcm_521_23
- World Health Organization. Water, sanitation and hygiene (WASH). Available from: https://www.who.int/health-topics/water-sanitation-and-hygiene-wash#tab=tab_1
- Centers for Disease Control and Prevention. Global Water, Sanitation, and Hygiene (WASH). 2025 Jul 29. Available from: https://www.cdc.gov/global-water-sanitation-hygiene/about/index.html
- Peterson EA, Lange JE, Buckley GJ, editors. Investing in global health systems: sustaining gains, transforming lives. Available from: https://www.kumc.edu/documents/international/eBOOK-%20Investing%20in%20Global%20Health%20System-Sustaining%20Gains%20Transforming%20Lives.pdf
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